DVM (Doctor Of Veterinary Medicine) Exam

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What is the primary metabolic reason that most non-steroidal anti-inflammatory drugs (NSAIDs) must be used with extreme caution and at specific, validated doses and intervals in cats?

They are highly susceptible to NSAID-induced hepatotoxicity. They frequently develop severe gastric ulceration after a single dose. They have a relative deficiency in the hepatic enzyme glucuronyl transferase. They are unable to produce protective prostaglandins in the stomach.

Correct Answer:

They have a relative deficiency in the hepatic enzyme glucuronyl transferase.

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