DNA Structure, Function, And Replication In Biology Practice Test

What role do single-strand binding proteins (SSBs) play during replication?

Stabilize and protect single-stranded DNA, preventing secondary structures and re-annealing Synthesize RNA primers Seal nicks between fragments Unwind the helix

Correct Answer:

Stabilize and protect single-stranded DNA, preventing secondary structures and re-annealing

Explanation:

During DNA replication, the two strands of the double helix are unwound to create single-stranded templates. Single-strand binding proteins bind to these exposed strands, coating them to keep them extended and accessible. This prevents the strands from forming secondary structures, like hairpins, and from re-annealing to each other, which would obstruct the DNA polymerases that must read the templates. SSBs also protect the exposed DNA from nucleases. While primase makes RNA primers, ligase seals nicks, and helicase unwinds the helix, the primary role of SSBs is to stabilize and protect the single-stranded DNA so replication can proceed smoothly.

Access more questions from this quiz

Continue to DNA Structure, Function, and Replication in Biology Practice Test for more practice questions and the full quiz experience.

Access More Questions