DABAT Practice Questions - Diplomate Of The American Board Of Applied Toxicology (DABAT) Exam

What is the mechanism of action of fomepizole in the treatment of toxic alcohol ingestion?

It enhances renal excretion of the toxic alcohol It inhibits alcohol dehydrogenase, preventing formation of toxic metabolites It directly neutralizes the toxic metabolites of methanol and ethylene glycol It increases the activity of aldehyde dehydrogenase

Correct Answer:

It inhibits alcohol dehydrogenase, preventing formation of toxic metabolites

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