Pediatric Settings Road Map Practice Test

What is the maximum single dose of intramuscular epinephrine recommended for pediatric anaphylaxis?

0.15 mg 0.3 mg 0.5 mg 1.0 mg

Correct Answer:

0.3 mg

Explanation:

In pediatric anaphylaxis, epinephrine given by intramuscular injection is dosed by weight, typically 0.01 mg/kg, but there is a safety ceiling of 0.3 mg per dose. This cap means the largest single dose you would give at once is 0.3 mg, even if a higher weight-based calculation would suggest more. You can repeat the dose every 5–15 minutes if symptoms persist, up to clinical improvement. In practice, auto-injectors provide fixed doses—commonly 0.15 mg for smaller children and 0.3 mg for larger children and adults—but you should not exceed 0.3 mg per injection. Administer into the mid-anterolateral thigh using the 1:1000 concentration.

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