Ultrasound Physics II Practice Exam

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What is the key difference between fundamental and harmonic imaging regarding tissue interaction?
Correct Answer:
Fundamental uses transmitted frequency; harmonic imaging uses nonlinear tissue response to generate harmonics, improving contrast and resolution
Explanation:
Fundamental imaging relies on the tissue responding in a linear way to the transmitted ultrasound, so the echoes come back at the same frequency that was sent. Harmonic imaging, by contrast, uses the tissue’s nonlinear response to the ultrasound to generate new frequencies (multiples of the transmitted frequency, with the second harmonic being the most used). The image is formed from these harmonic components, which tends to improve contrast and resolution and reduce certain artifacts. This is why the correct description is that fundamental uses the transmitted frequency, while harmonic imaging relies on nonlinear tissue generation of harmonics to provide the image.

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