Acrp Practice Test & Exam Prep

What is the difference between per-protocol (PP) and intent-to-treat (ITT) analysis in clinical trials?

PP includes all enrolled participants; ITT includes only completers ITT includes all randomized participants regardless of compliance; PP includes only those who completed per protocol Both methods are identical in practice PP is used for safety analysis; ITT is used for efficacy only

Correct Answer:

ITT includes all randomized participants regardless of compliance; PP includes only those who completed per protocol

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