AAFM Boards Dermatology Practice Test

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Which drug is effective in treating severe cases of staph folliculitis caused by MRSA?
Correct Answer:
Bactrim
Explanation:
Bactrim, which is a combination of trimethoprim and sulfamethoxazole, is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA). MRSA is known for its resistance to many standard antibiotics, making the treatment of infections, including severe cases of staph folliculitis, challenging. Bactrim works by inhibiting bacterial folic acid synthesis, which is essential for bacterial growth and reproduction, effectively controlling the infection. In contrast, the other options do not offer the same efficacy against MRSA. Dapoxetine is primarily an antidepressant used for premature ejaculation, and it does not possess antibacterial properties. Dicloxacillin is effective against methicillin-sensitive Staphylococcus aureus (MSSA) but not effective against MRSA due to the bacterial resistance. Ciprofloxacin, while a fluoroquinolone antibiotic effective against various bacterial infections, is not the first-line treatment for MRSA and may not be as effective as Bactrim in this specific case. Thus, for severe cases of staph folliculitis caused by MRSA, Bactrim is clearly the appropriate choice.

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