University Of Central Florida (UCF) PCB3233 Immunology Practice Exam 1

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What are the three main functions of the complement system?
Correct Answer:
Enhance opsonization, promote inflammation, and directly lyse pathogens
Explanation:
The complement system plays a critical role in the immune response, and the correct answer identifies its three main functions effectively. Firstly, the enhancement of opsonization allows the complement proteins to coat pathogens, making them more recognizable and easier for phagocytic cells, like macrophages and neutrophils, to engulf and destroy. This tagging process significantly boosts the efficiency of the immune response against invading microorganisms. Secondly, the promotion of inflammation is accomplished by various complement components that interact with immune cells and blood vessels. This process involves the release of inflammatory mediators, leading to increased blood flow and attracting more immune cells to the site of infection, which is essential for effectively managing and eliminating pathogens. Lastly, the ability of the complement system to directly lyse pathogens is crucial for its function. Certain complement proteins form the Membrane Attack Complex (MAC), which creates pores in the membranes of target cells, leading to their lysis and subsequent death. This mechanism is particularly effective against certain bacteria and parasites. In contrast, the other options do not accurately represent the primary functions of the complement system. For instance, stimulating T cell activation or activating B cells focuses on different branches of the adaptive immune response rather than the complement system itself. Similarly, regulating blood flow and

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