ABOG Reproductive Endocrinology And Infertility Practice Questions - ABOG Reproductive Endocrinology And Infertility Subspecialty Certifying Examination Exam

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The hypothalamic-pituitary-ovarian axis relies on pulsatile GnRH secretion from the arcuate nucleus. What frequency of GnRH pulses preferentially stimulates FSH over LH release?

Slow-frequency pulses (every 90-120 min) favor FSH release Fast-frequency pulses (every 60 min) favor FSH release Continuous GnRH administration preferentially releases FSH GnRH pulse frequency does not affect FSH vs LH release

Correct Answer:

Slow-frequency pulses (every 90-120 min) favor FSH release

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