Arab Board Anesthesia Final Written Practice Questions - Arab Board Of Health Specializations (ABHS) Anesthesia And Intensive Care Final Written Examination Exam

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Ten minutes following cardiopulmonary bypass separation, protamine sulfate is infused to reverse heparin. Within two minutes, the patient develops sudden severe pulmonary hypertension, elevated central venous pressure, and acute systemic arterial hypotension with right ventricular distension. What is the most likely diagnosis?

Type I protamine reaction due to rapid infusion Type II protamine anaphylactic reaction mediated by IgE Type III protamine reaction mediated by thromboxane A2 release Acute left ventricular anterior wall myocardial infarction

Correct Answer:

Type III protamine reaction mediated by thromboxane A2 release

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