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A patient on IV heparin develops a platelet count drop from 250 to 85 × 10⁹/L after 7 days with new DVT. 4Ts score is 7. Which HIT test should be ordered first?

Heparin-platelet factor 4 (PF4) ELISA (anti-PF4/heparin antibodies) as screening, followed by serotonin release assay (SRA) if positive/intermediate Platelet function tests only D-dimer Fibrinogen level

Correct Answer:

Heparin-platelet factor 4 (PF4) ELISA (anti-PF4/heparin antibodies) as screening, followed by serotonin release assay (SRA) if positive/intermediate

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