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Scope Of CRNA Exam 1 Practice
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Sugammadex reverses which agents?
Succinylcholine
Atracurium
Rocuronium and Vecuronium
Mivacurium
Reveal Answer
Correct Answer:
Rocuronium and Vecuronium
Explanation:
Sugammadex reverses aminosteroidal nondepolarizing neuromuscular blockers by encapsulating the drug molecules, which lowers their free concentration at the neuromuscular junction and allows acetylcholine to outcompete what remains at the receptor. This mechanism specifically targets rocuronium and vecuronium, so reversal is effective for these two agents. It does not reverse succinylcholine, a depolarizing blocker, nor benzylisoquinolinium agents like atracurium and mivacurium, because they do not bind effectively to sugammadex. In practice, this makes sugammadex a rapid reversal option for rocuronium- or vecuronium-induced blockade.
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