ABPath Hematopathology Practice Questions - ABPath Hematopathology Subspecialty Certification Exam

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Peripheral blood flow cytometry in a 70-year-old with lymphocytosis (ALC 15,000/μL) shows a B-cell clone with CD19+, CD5+, CD23+, CD20 dim, FMC7-, surface kappa dim. The diagnosis is:

Monoclonal B-cell lymphocytosis (MBL) Chronic lymphocytic leukemia (CLL) — because the absolute monoclonal B-cell count is ≥5,000/μL per iwCLL 2018 criteria Mantle cell lymphoma Follicular lymphoma

Correct Answer:

Chronic lymphocytic leukemia (CLL) — because the absolute monoclonal B-cell count is ≥5,000/μL per iwCLL 2018 criteria

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