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Nightingale Pathophysiology Practice Test

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Osteomalacia is best described as which of the following?
Correct Answer:
Osteomalacia
Explanation:
The key idea is defective mineralization of bone in adults. In osteomalacia, the mineralization of the osteoid is impaired, so bones become soft and prone to pain and fractures, especially with minimal trauma. This condition is the adult counterpart to rickets, which affects growing bone in children. The other conditions describe different problems: osteoporosis is a loss of bone mass with normal mineralization; osteogenesis imperfecta is a genetic defect in collagen that makes bones fragile. From the options, the best description is the condition itself—osteomalacia—because it precisely names the problem: defective mineralization of bone matrix in adults.

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