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NY01 Version 2 Practice Test

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Klinefelter syndrome is characterized by tall stature, infertility, and gynecomastia; which karyotype is involved?
Correct Answer:
Klinefelter syndrome
Explanation:
Having an extra X chromosome in a male leads to Klinefelter syndrome. The characteristic karyotype is 47,XXY, meaning two X chromosomes and one Y in each cell. That extra X disrupts testicular development and hormone balance, which explains infertility and gynecomastia, while the overall effect often includes tall stature. Down syndrome is due to trisomy 21 and has its own distinct features; Turner syndrome involves missing one X chromosome in females (45,X) and presents differently; Kallmann syndrome is a hormone-related condition not defined by a specific sex-chromosome pattern. So the described scenario points to the 47,XXY karyotype.

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