DABCC Practice Questions - Diplomate Of The American Board Of Clinical Chemistry Exam

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In tandem mass spectrometry (LC-MS/MS), what does multiple reaction monitoring (MRM) measure to achieve high specificity?

Only the molecular weight of the intact analyte Total ion current across the full mass range A specific precursor ion fragmented to a specific product ion transition The UV absorbance of eluting peaks

Correct Answer:

A specific precursor ion fragmented to a specific product ion transition

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