SPEC Chiropractic Practice Exam

Which two selective serotonin reuptake inhibitors are explicitly named in the material?

Citalopram and Paroxetine Sertraline and Fluoxetine Venlafaxine and Duloxetine Bupropion and Mirtazapine

Correct Answer:

Sertraline and Fluoxetine

Explanation:

The main idea is recognizing which drugs are selective serotonin reuptake inhibitors (SSRIs) and which ones the material actually names as examples. Sertraline and Fluoxetine are both SSRIs, and the material explicitly names these two as the representatives of that class, which is why they’re the best fit. SSRIs work by blocking the serotonin transporter, increasing serotonin levels in the synaptic cleft. The other options mix in different antidepressant classes: Venlafaxine and Duloxetine are SNRIs (not pure SSRIs), while Bupropion and Mirtazapine are not SSRIs at all. Although Citalopram and Paroxetine are SSRIs, the material doesn’t name that pair, so they aren’t the two SSRIs being referenced here.

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