Angola 12th Grade Biology National Exam Practice Questions - Angola 12th Grade National Examination - Biology (Exame Nacional Da 12.a Classe Biologia) Exam

Simple diffusion requires ATP hydrolysis, whereas facilitated diffusion operates without metabolic energy. Simple diffusion moves solutes against their concentration gradient, whereas facilitated diffusion moves solutes down their gradient. Simple diffusion moves non-polar solutes directly through the lipid bilayer, whereas facilitated diffusion uses channel or carrier proteins. Simple diffusion only occurs in plant cells, whereas facilitated diffusion is restricted to animal cells.