VWO Biologie Practice Questions - Netherlands VWO Biologie - Centraal Examen And Schoolexamen

How does a non-competitive inhibitor affect an enzyme-catalyzed reaction compared to a competitive inhibitor?

It binds to the active site and increases Km without altering Vmax. It binds to an allosteric site, reducing Vmax while leaving Km largely unchanged. It competes directly with the substrate for active site binding, raising Vmax. It permanently degrades the substrate molecule before it can reach the active site.

Correct Answer:

It binds to an allosteric site, reducing Vmax while leaving Km largely unchanged.

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