Pharmacology IV – Headache Therapeutics Practice Test

How do CGRP monoclonal antibodies become prescribed in terms of administration?

Intramuscular injections daily Subcutaneous injections at regular intervals (monthly or quarterly) depending on agent Oral tablets daily Intravenous infusions weekly

Correct Answer:

Subcutaneous injections at regular intervals (monthly or quarterly) depending on agent

Explanation:

The main idea is that CGRP monoclonal antibodies are given by subcutaneous injections at regular intervals, not daily pills or weekly infusions. Most of these agents are dosed monthly by subcutaneous injection, with fremanezumab offering either monthly or quarterly schedules depending on the regimen. An important exception is eptinezumab, which is given by intravenous infusion every 12 weeks. So the typical prescription pattern is subcutaneous injections at monthly or quarterly intervals, depending on the specific agent.

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