ARRT CT Practice Questions - ARRT Computed Tomography (Postprimary) Exam

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Case 002 (Contrast Allergy): A 45-year-old female is scheduled for a CT pulmonary angiography (CTPA) to rule out pulmonary embolism. She reports a prior moderate allergic reaction (hives and facial swelling) to iodinated contrast during a previous CT. What is the recommended pre-medication protocol?

Administer 50 mg oral prednisone at 13 hours, 7 hours, and 1 hour before contrast injection plus 50 mg oral diphenhydramine 1 hour before. Give 25 mg IV diphenhydramine immediately before injection without corticosteroids. Use a different brand of iodinated contrast without pre-medication since the allergy is brand-specific. Cancel the CTPA entirely and order a ventilation-perfusion scan instead.

Correct Answer:

Administer 50 mg oral prednisone at 13 hours, 7 hours, and 1 hour before contrast injection plus 50 mg oral diphenhydramine 1 hour before.

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