Concussion Management Practice Exam

An energy crisis after concussion is described as resulting from hypermetabolism in combination with which change?

Hypometabolism Neuroinflammation Excitotoxicity Hypermetabolism

Correct Answer:

Hypermetabolism

Explanation:

After a concussion, the brain’s energy needs rise because neurons work harder to restore ion gradients and restore normal function, creating a hypermetabolic state. If, at the same time, the brain’s metabolic capacity or blood flow to the injured areas is reduced, the higher energy demand cannot be met. This mismatch—the brain trying to burn more energy while its metabolism remains limited—drives the energy crisis. The accompanying change described here is hypometabolism. Neuroinflammation and excitotoxicity are part of the broader injury process, but the defining metabolic mismatch is the combination of increased demand with reduced metabolic activity.

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