ABPS Geriatric Medicine Practice Questions - ABPS Geriatric Medicine Certification Examination Exam

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An 82-year-old woman with mild dementia is started on diphenhydramine 25 mg nightly for insomnia. According to the AGS 2023 Beers Criteria, why is this medication potentially inappropriate?

It causes hypoglycemia in older adults It is a strong anticholinergic associated with cognitive impairment, delirium, and falls It is contraindicated with cholinesterase inhibitors It is metabolized by CYP3A4 and interacts with grapefruit

Correct Answer:

It is a strong anticholinergic associated with cognitive impairment, delirium, and falls

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