Ambulatory Care Nurse – Board Certified (AMB-BC) Practice Test

ACTH primarily stimulates hormone production in which gland?

Thyroid gland Adrenal cortex Pancreas Pituitary gland

Correct Answer:

Adrenal cortex

Explanation:

ACTH, or adrenocorticotropic hormone, acts on the adrenal cortex to stimulate the production and release of glucocorticoids, especially cortisol (with some effect on mineralocorticoids). This is part of the hypothalamic-pituitary-adrenal axis that helps regulate stress responses, metabolism, and immune function. The thyroid is controlled by TSH, the pancreas by insulin and glucagon, and the pituitary gland is the source of ACTH—not its target. So the adrenal cortex is the gland primarily stimulated by ACTH.

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