ABPath Pediatric Pathology Practice Questions - ABPath Pediatric Pathology Subspecialty Certification Examination Exam

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A second-trimester placenta shows hydropic villi of markedly variable size with trophoblast hyperplasia and cistern formation. IHC for p57 (CDKN1C) shows no staining in cytotrophoblast or villous stromal cells. Which diagnosis?

Complete hydatidiform mole Partial hydatidiform mole Placental mesenchymal dysplasia Spontaneous abortion with hydropic change

Correct Answer:

Complete hydatidiform mole

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