Bac Série D Côte D'Ivoire Practice Questions - Baccalauréat Série D (Sciences De La Vie Et De La Terre) - Côte D'Ivoire Exam

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A point mutation in the coding sequence of a gene replaces the codon 5'-UAC-3' (encoding Tyrosine) with 5'-UAA-3'. What type of mutation is this, and what is its expected phenotypic impact on the polypeptide?

Silent mutation; no change in polypeptide length or sequence Missense mutation; substitution of a single amino acid with altered folding Frameshift mutation; alteration of the entire downstream reading frame Nonsense mutation; premature termination resulting in a truncated, nonfunctional protein

Correct Answer:

Nonsense mutation; premature termination resulting in a truncated, nonfunctional protein

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