BCIDP Practice Questions - Board Certified Infectious Diseases Pharmacist Exam

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A patient with MRSA bacteremia has a vancomycin trough of 8 mcg/mL after 48 hours of therapy. Based on current IDSA/ASHP/SIDP vancomycin guidelines, what is the recommended approach?

Continue current dosing as the trough is within therapeutic range Target an AUC/MIC ratio of 400-600 using Bayesian software or first-order PK calculations Increase the dose to achieve a trough of 20-25 mcg/mL Discontinue vancomycin and switch to oral therapy

Correct Answer:

Target an AUC/MIC ratio of 400-600 using Bayesian software or first-order PK calculations

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