SPLE (Pharmacist) Practice Questions - Saudi Pharmacist Licensure Examination (SPLE - Pharmacist) (CBT Via Prometric) Exam

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A patient with a known IgE-mediated penicillin allergy receives a beta-lactam and develops urticaria, bronchospasm and hypotension within minutes. According to the Gell and Coombs classification, what type of hypersensitivity reaction is this?

Type II (antibody-mediated cytotoxic) Type III (immune complex) Type I (immediate, IgE-mediated) Type IV (delayed, T-cell mediated)

Correct Answer:

Type I (immediate, IgE-mediated)

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