CFPC CAC Palliative Care Practice Questions - College Of Family Physicians Of Canada Certificate Of Added Competence In Palliative Care Assessment Exam

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A palliative patient with end-stage renal disease (eGFR 14 mL/min/1.73m²) requires opioid analgesia for severe nociceptive pain. Which opioid regimen is safest to avoid neurotoxic metabolite accumulation?

Hydromorphone or fentanyl at reduced doses with extended dosing intervals Morphine sustained-release 30 mg twice daily Codeine 60 mg every 4 hours Meperidine 100 mg every 4 hours

Correct Answer:

Hydromorphone or fentanyl at reduced doses with extended dosing intervals

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