ABFM Palliative Care Practice Questions - ABFM Hospice And Palliative Medicine Certificate Of Added Qualifications (CAQ) Exam

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A family physician sees a 71-year-old woman with metastatic colon cancer in clinic. She is taking morphine sustained-release 30 mg PO every 12 hours (60 mg/day) with good pain control but persistent, refractory nausea attributed to morphine. You rotate to oral hydromorphone. Using standard equianalgesic dosing and accounting for incomplete cross-tolerance, what is the most appropriate starting daily dose of oral hydromorphone?
Correct Answer:
Hydromorphone 7.5-11 mg/day (divided Q4H)

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