NCLEX Pharmacology Cardiovascular Drugs Practice Test

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A client is being changed from an injectable anticoagulant to an oral anticoagulant. Which anticoagulant is administered orally?
Correct Answer:
Warfarin
Explanation:
Oral versus injectable anticoagulants. Warfarin is the anticoagulant given by mouth. It works by inhibiting vitamin K-dependent production of clotting factors II, VII, IX, and X, which makes it suitable for long-term oral anticoagulation. Because warfarin takes several days to reach full effect, patients are often bridged with a parenteral anticoagulant until the INR is in the therapeutic range. The other agents listed are not oral: enoxaparin is given by subcutaneous injection; bivalirudin and lepirudin are direct thrombin inhibitors administered intravenously. So, when switching from an injectable anticoagulant to an oral one, warfarin is the correct oral option.

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