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Basic And Clinical Sciences Examination (BCSE)

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A biopsy from a skin mass on an 8-year-old Boxer is submitted for histopathology. The pathologist describes 'sheets of round cells with distinct cell borders, abundant eosinophilic granular cytoplasm, and central, round nuclei.' There is minimal pleomorphism and a low mitotic rate. Mast cell granules are not observed with routine H&E staining but would likely be prominent with which special stain?
Correct Answer:
Toluidine Blue

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