FVH Kleintiere Practice Questions - Fachtierarzt FVH Für Kleintiere (Switzerland) Exam

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A 9-year-old female spayed Dachshund with pituitary-dependent hyperadrenocorticism (PDH) has been receiving trilostane (1.5 mg/kg PO q12h) for 4 weeks. What is the standard consensus protocol for monitoring treatment efficacy and avoiding hypoadrenocorticism?

Evaluate clinical response (polyuria/polydipsia, appetite) combined with a pre-pill serum cortisol or post-pill ACTH stimulation test performed 3 to 4 hours after trilostane administration Perform a 24-hour urine cortisol-to-creatinine ratio (UCCR) alone, as serum cortisol concentrations do not correlate with adrenal enzyme inhibition Measure plasma endogenous ACTH (eACTH) 12 hours post-pill to verify complete down-regulation of pituitary corticotroph adenoma secretion Perform a high-dose dexamethasone suppression test (HDDST) every 3 months to assess adrenocortical reserve capacity

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Evaluate clinical response (polyuria/polydipsia, appetite) combined with a pre-pill serum cortisol or post-pill ACTH stimulation test performed 3 to 4 hours after trilostane administration

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