FRCS Urol Practice Questions - Intercollegiate Specialty Fellowship Examination In Urology (FRCS Urol) Exam

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A 70-year-old man with castration-resistant prostate cancer has bone-only metastases and rising PSA despite abiraterone. Genomic testing reveals a germline BRCA2 mutation. Which targeted agent is specifically indicated for BRCA-mutated metastatic CRPC?

Olaparib (a PARP inhibitor) Cabazitaxel Radium-223 Sipuleucel-T

Correct Answer:

Olaparib (a PARP inhibitor)

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