ABIM Infectious Disease Practice Questions - American Board Of Internal Medicine Infectious Disease Subspecialty Certification Exam

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A 44-year-old woman presents with fever 39°C, flank pain, and dysuria. She is hemodynamically stable and can tolerate oral intake. Urine culture is pending. Which empiric outpatient regimen is appropriate for acute uncomplicated pyelonephritis?

Ciprofloxacin 500 mg BID × 7 days (or after an IV ceftriaxone 1 g loading dose if local fluoroquinolone resistance >10%) Nitrofurantoin 100 mg BID × 5 days Fosfomycin 3 g PO × 1 dose Amoxicillin 500 mg TID × 14 days

Correct Answer:

Ciprofloxacin 500 mg BID × 7 days (or after an IV ceftriaxone 1 g loading dose if local fluoroquinolone resistance >10%)

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