ANCC Ambulatory Care Nursing Certification Exam

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A 65-year-old male, recently started on high-intensity atorvastatin for secondary prevention of ASCVD, calls the clinic complaining of new-onset, bilateral thigh pain that began a week ago. He denies injury, and his creatine kinase (CK) level is within the normal range. What is the most appropriate next step in managing this patient's symptoms?

Reassure the patient that this is a benign side effect and advise him to continue the medication. Hold the atorvastatin for 2-4 weeks and, if symptoms resolve, re-challenge with the same or a lower dose. Immediately switch to a different high-intensity statin, such as rosuvastatin. Refer the patient to a rheumatologist for a full workup of myopathy.

Correct Answer:

Hold the atorvastatin for 2-4 weeks and, if symptoms resolve, re-challenge with the same or a lower dose.

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