Arab Board Dermatology Clinical Practice Questions - Arab Board Dermatology And Venereology Final Clinical And Oral Exam (ABHS) Exam

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A 54-year-old woman with end-stage renal disease on hemodialysis and secondary hyperparathyroidism develops intensely painful, violaceous, retiform purpuric plaques with central necrosis and eschar formation on both thighs. Skin biopsy demonstrates medial calcification and intimal fibroblastic proliferation of small subcutaneous arterioles with thrombosis. Which of the following is the most appropriate first-line pharmacologic therapy for this condition?
Correct Answer:
Intravenous sodium thiosulfate

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