Afghanistan Pharmacy Technician Exit Exam Practice Questions - Afghanistan Pharmacy Technician Exit Exam (Institutes Of Health Sciences) Exam

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A 52-year-old hypertensive patient who was started on enalapril 10 mg daily 3 weeks ago presents to the clinic complaining of a persistent, non-productive dry cough. What is the physiological mechanism responsible for this adverse drug reaction?

Direct allergic hypersensitivity causing laryngeal bronchospasm Accumulation of bradykinin and substance P in the respiratory tract due to ACE inhibition Excessive accumulation of angiotensin II causing pulmonary capillary vasoconstriction Inhibition of surfactant production by alveolar type II pneumocytes

Correct Answer:

Accumulation of bradykinin and substance P in the respiratory tract due to ACE inhibition

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