Arab Board Dermatology Clinical Practice Questions - Arab Board Dermatology And Venereology Final Clinical And Oral Exam (ABHS) Exam

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A 35-year-old man develops widespread non-follicular superficial pustules on a background of edematous erythema within 48 hours of starting amoxicillin-clavulanate. Blood tests show marked leukocytosis with neutrophilia (18 x 10^9/L). Which chemokine and cytokine axis is primarily responsible for the rapid recruitment of neutrophils in Acute Generalized Exanthematous Pustulosis (AGEP)?
Correct Answer:
Interleukin-8 (CXCL8) produced by drug-specific T-cells

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