Dip Int Med(SA) Practice Questions - Diploma In Internal Medicine Of The College Of Physicians Of South Africa Dip Int Med(SA) Exam

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A 28-year-old pregnant woman (26 weeks gestation) is admitted to a district hospital with a severe asthma exacerbation. SpO2 is 90% on room air, peak expiratory flow rate (PEFR) is 40% of predicted, and she has marked intercostal retractions. In addition to high-flow oxygen and frequent nebulised Salbutamol, which systemic corticosteroid regimen is indicated?

Systemic corticosteroids must be strictly avoided during pregnancy due to teratogenicity Oral Prednisone 40-50 mg daily (or IV Hydrocortisone 100 mg 6-hourly) for 5-7 days Inhaled Fluticasone high-dose monotherapy without any systemic steroids Single dose of IM Dexamethasone 6 mg only for fetal lung maturation

Correct Answer:

Oral Prednisone 40-50 mg daily (or IV Hydrocortisone 100 mg 6-hourly) for 5-7 days

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