AOBOS Orthopedics Practice Questions - AOBOS Orthopedic Surgery Certifying Examination Exam

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A 25-year-old man presents 3 hours after a motorcycle crash with an open midshaft tibia fracture (Gustilo-Anderson type IIIA). The most appropriate initial antibiotic regimen includes:

Vancomycin alone First-generation cephalosporin (e.g., cefazolin) within 1 hour Daptomycin alone No antibiotics until cultures return

Correct Answer:

First-generation cephalosporin (e.g., cefazolin) within 1 hour

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