Título Em Hematologia E Hemoterapia Practice Questions - Título De Especialista Em Hematologia E Hemoterapia (ABHH AMB) Exam

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A 22-year-old male with known Sickle Cell Disease (Anemia Falciforme - HbSS) is admitted with fever (38.8°C), acute pleuritic chest pain, tachypnea (RR 28/min), and an oxygen saturation of 88% on ambient air. Chest radiography reveals a new alveolar consolidation in the right lower lobe. In accordance with Brazilian Clinical Protocols (PCDT da Doença Falciforme), which emergency therapeutic approach is indicated?

Empiric broad-spectrum intravenous antibiotics (including macrolide coverage), aggressive fluid hydration, supplemental oxygen, and prompt red blood cell transfusion (simple or exchange) targeting Hb ~10 g/dL. High-dose corticosteroids alone, strict fluid restriction, and immediate prophylactic anticoagulation with full-dose warfarin. Routine therapeutic phlebotomy to reduce blood viscosity followed by high-dose aspirin. Immediate emergency splenectomy to prevent recurrent splenic sequestration crisis.

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