Arab Board Surgery Final Written Practice Questions - Arab Board General Surgery Final Written Examination Exam

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A 61-year-old man with long-standing Barrett esophagus is diagnosed with a biopsy-proven distal esophageal adenocarcinoma. Endoscopic ultrasound (EUS) and CT of the chest and abdomen stage the lesion as cT3N1M0. What is the standard evidence-based curative-intent treatment strategy?

Immediate upfront Ivor Lewis esophagectomy without neoadjuvant therapy Neoadjuvant chemoradiation (CROSS regimen) followed by planned surgical esophagectomy Definitive chemoradiotherapy alone without surgical resection Endoscopic submucosal dissection (ESD) followed by surveillance endoscopy

Correct Answer:

Neoadjuvant chemoradiation (CROSS regimen) followed by planned surgical esophagectomy

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