Afghanistan Pharmacy Technician Exit Exam Practice Questions - Afghanistan Pharmacy Technician Exit Exam (Institutes Of Health Sciences) Exam

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In paracetamol (acetaminophen) toxicity, hepatic necrosis occurs due to the accumulation of a toxic reactive metabolite. Which metabolite is responsible, and which specific antidote is administered to replenish hepatic glutathione stores?

N-acetyl-p-benzoquinone imine (NAPQI); treated with N-acetylcysteine (NAC) Para-aminophenol; treated with flumazenil Glucuronide conjugate; treated with deferoxamine Acetaldehyde; treated with fomepizole

Correct Answer:

N-acetyl-p-benzoquinone imine (NAPQI); treated with N-acetylcysteine (NAC)

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