ABCRS Practice Questions - American Board Of Colon And Rectal Surgery Certification Exam

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In the OPRA trial, patients with locally advanced rectal cancer were randomized to induction chemotherapy followed by chemoradiation vs. chemoradiation followed by consolidation chemotherapy. What was the key finding?

Induction chemo improved overall survival Consolidation chemo after CRT produced higher rates of organ preservation No difference in complete clinical response Consolidation chemo had higher toxicity and worse DFS

Correct Answer:

Consolidation chemo after CRT produced higher rates of organ preservation

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