Título De Especialista Em Anestesiologia (SBA AMB) Practice Questions - TEA - Título De Especialista Em Anestesiologia (Sociedade Brasileira De Anestesiologia AMB) Exam

Competitive antagonism of central NMDA receptors leading to dissociative anesthesia, with exclusive renal excretion. Positive allosteric modulation and direct activation of GABA-A receptor beta-subunits, resulting in increased chloride conductance, with a systemic clearance that exceeds hepatic blood flow. Selective agonism of central alpha-2 adrenergic receptors in the locus coeruleus, accompanied by active glucuronide metabolites that prolong sedation. Irreversible blockade of voltage-gated sodium channels in the reticular activating system, with zero-order elimination kinetics.