Therapy Radiopharmaceuticals Practice Test

Which of the following is NOT part of Sr-89 chloride normal biodistribution?

Bone surface Bone marrow Lower GI Liver

Correct Answer:

Liver

Explanation:

Sr-89 chloride behaves like calcium and concentrates in bone mineral, especially on surfaces where new bone is formed. Its normal biodistribution is largely skeletal, with uptake at bone surfaces tied to osteoblastic activity and only minimal soft-tissue involvement. It does not normally accumulate in the liver, so hepatic uptake would indicate an abnormal distribution. Therefore, the liver is not part of Sr-89 chloride’s normal biodistribution.

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