The Nursing Process In Pharmacology Practice Exam

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Why is therapeutic drug monitoring often used for drugs with a narrow therapeutic index?
Correct Answer:
It estimates drug manufacturing cost.
Explanation:
Drugs with a narrow therapeutic index have a small margin between effective and toxic levels, so small differences in how a person processes the drug can push them from benefit to harm. Therapeutic drug monitoring measures the drug’s concentration in the blood and uses that information to keep levels within a defined therapeutic window. By checking levels and adjusting dose or dosing interval, clinicians tailor therapy to the individual, maximizing efficacy while minimizing toxicity. This is especially important for medications like lithium, digoxin, certain anticonvulsants, and some antibiotics, where toxicity can be serious if levels drift even slightly. The other choices don’t pertain to monitoring blood concentrations or adjusting therapy based on patient-specific drug levels.

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