Special Purpose Examination (SPEX) [spex-exam]

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A 35-year-old married woman contacts you since her older sister recently received a breast cancer diagnosis and her mother passed away from the disease in her 40s. She is Jewish, and her Polish-born grandparents are. She is interested in learning what she may do to reduce her risk of contracting the illness. She has a child who is 5 years old, is in good health, and plans to have one or two more children in the future. It's normal to examine your breasts. She tested positive for the BRCA2 gene, according to genetic testing. Though it is brought up, she declines to consider a bilateral mastectomy. What would be the most effective strategy for handling her case?

Schedule an MRI of the breast and if negative, annual examination only Schedule an MRI of the breast and if negative, start tamoxifen Refer to a radiation therapist for prophylactic radiation treatment to both breasts Schedule a mammogram and if negative, order an annual mammogram

Correct Answer:

Schedule an MRI of the breast and if negative, start tamoxifen

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