Review Of Related Disease (RRD) 5 Practice Exam

Which of the following best reflects the S&S of thrombocytopenia:

Fever and night sweats Weight loss Petechiae, purpura, ecchymosis Jaundice

Correct Answer:

Petechiae, purpura, ecchymosis

Explanation:

Low platelets impair the formation of the platelet plug, the first step in stopping bleeding. When platelets are deficient, small blood vessels leak into the skin and mucous membranes, producing the classic skin findings: tiny pinpoint hemorrhages (petechiae), larger patches (purpura), and even larger bruises (ecchymosis). These signs directly reflect a problem with platelet numbers and primary hemostasis. Fever with night sweats, weight loss, and jaundice point to other processes such as infection, malignancy, liver disease, or hemolysis, and are not characteristic manifestations of thrombocytopenia. If you see petechiae, purpura, or ecchymosis, it’s a clue to check the platelet count and assess for thrombocytopenia.

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